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MS-LS3-2NGSS*ScienceLife ScienceGrades 6-8

MS-LS3-2: Modeling Asexual and Sexual Reproduction and Genetic Variation

In plain English: MS-LS3-2 is the NGSS middle school performance expectation that asks students to develop and use a model, such as a Punnett square, a diagram or a simulation, to explain why asexual reproduction gives offspring with identical genetic information while sexual reproduction gives offspring with genetic variation. It is usually taught in grade 7 or 8 life science.

Develop and use a model to describe why asexual reproduction results in offspring with identical genetic information and sexual reproduction results in offspring with genetic variation.

Clarification Statement: Emphasis is on using models such as Punnett squares, diagrams, and simulations to describe the cause and effect relationship of gene transmission from parent(s) to offspring and resulting genetic variation.

Next Generation Science Standards · Disciplinary Core Idea: Heredity: Inheritance and Variation of Traits · Official standard

01

Lesson Plan

45-65 min

Overview

Students develop and use models to explain why offspring made by asexual reproduction (one parent) carry genetic information identical to their parent, while offspring made by sexual reproduction (two parents) show genetic variation. They draw chromosome diagrams, build Punnett squares, run a bean-draw simulation for a fictional animal, root plant cuttings and compare them with seedlings, and critique other students' models. All examples use plants, animals or fictional organisms, never students or their families, and all data sets are invented for teaching.

The NGSS Clarification Statement says: "Emphasis is on using models such as Punnett squares, diagrams, and simulations to describe the cause and effect relationship of gene transmission from parent(s) to offspring and resulting genetic variation." MS-LS3-2 has no official Assessment Boundary. Students do the practice of developing and using models: they build each model, use it to predict outcomes, compare predictions with data and revise models that contain errors.

Learning Objectives

By the end of this lesson, students will be able to:

  • Use a diagram to explain why offspring of asexual reproduction have genetic information identical to their one parent
  • Use a diagram and a Punnett square to explain why offspring of sexual reproduction get half their genes from each parent and so vary
  • Use a Punnett square to predict the chances of allele combinations and compare predictions with data
  • Run and interpret a simulation of gene transmission, and critique models that show it incorrectly

Prior Knowledge Required

Students should already be comfortable with:

  • Plants and animals have life cycles that include reproduction 3-LS1-1
  • Traits are inherited, and individuals of the same kind vary 3-LS3-1
  • Genes on chromosomes code for proteins that affect traits MS-LS3-1
  • Probability as a number from 0 to 1 7.SP.C.5

Lesson Procedure

45-65 minutes of class time across 5 phases.

  1. Warm-Up5-10 minutes

    Show two photos: a tray of young spider-plant offshoots (baby plants on runners) that all look alike, and a litter of kittens from the same two parent cats with different coat colors and patterns.

    Warm-Up Prompt

    "The baby plants all look like their one parent. The kittens look different from each other and from their parents. What do you think is different about how each group was made? What would you need to know to test your idea?"

    Record ideas without correcting them. Students often say "one parent or two"; ask them why two parents would lead to differences. Return to this question at the end with the model.

  2. Direct Instruction15-20 minutes

    Key words. Genetic information is the set of genes an organism carries on its chromosomes (long strands of DNA in the nucleus). Most plant and animal cells have chromosomes in pairs, so they have two copies of each gene. The two copies may be the same or different versions; each version is called an allele and is written with a letter, such as A or a. Offspring are the young that an organism produces. In asexual reproduction, one parent makes offspring from its own body cells, which copy all of its chromosomes, so the offspring get identical genetic information. Offspring with identical genetic information are called clones. In sexual reproduction, two parents each make sex cells (eggs, sperm or pollen) that carry only one chromosome from each pair, chosen at random, and two sex cells join. So each offspring gets half its genes from each parent, in a new combination. Differences in genes among offspring are called genetic variation.

    Models. A Punnett square is a grid that shows every way the alleles of two parents can combine. One parent's alleles go across the top, the other's down the side, and each box is one equally likely outcome. An allele is dominant if one copy is enough to show its trait; the other allele is recessive, and its trait shows only with two copies. A simulation is a model that acts out a process with chance, such as drawing beans from bags. Diagram 1 compares the two kinds of reproduction. Rare mutations (changes in genes) can make even a clone slightly different; MS-LS3-1 covers them.

    • Asexual reproduction: plantlets on a kalanchoe leaf

      A kalanchoe plant grows tiny plantlets along the edges of its leaves. The plantlets drop off, root and grow into new plants. In the model, suppose the parent carries alleles A and a for one gene and B and b for another. A class potted 36 plantlets from one parent.

      Result: Each plantlet is made from the parent's own cells, which copy all of the parent's chromosomes. So every plantlet has Aa Bb, the same genetic information as the parent and as each other: 36 of 36 match (100%). With one parent and exact copies, there is no source of new gene combinations.

    • Sexual reproduction: a Punnett square for squash color (Diagram 2)

      In summer squash, the allele for white fruit (W) is dominant to the allele for yellow fruit (w): a plant with at least one W has white fruit. Two Ww plants, both with white fruit, are crossed. Invented data: 64 of their seeds grow into plants that bear fruit: 45 have white fruit and 19 have yellow fruit.

      Result: Punnett square: WW, Ww, Ww, ww, so 3 in 4 offspring are expected to have white fruit and 1 in 4 yellow. Expected: 64 × 3/4 = 48 white and 64 × 1/4 = 16 yellow. Observed 45 and 19 are close; real counts scatter around the prediction. The yellow plants have a trait that neither parent shows, because each got one w from each parent.

    • One plant, two ways: strawberry runners and strawberry seeds

      A strawberry plant with alleles Aa Bb sends out runners, stems that grow along the ground and root into new plants. It also makes seeds when its flowers are pollinated by another Aa Bb plant. A grower raises 12 runner plants and a tray of seedlings.

      Result: Runner plants: all 12 are Aa Bb, identical to the parent. Seedlings: for gene A alone, a Punnett square gives AA, Aa or aa (3 combinations), and the same for gene B, so there are 3 × 3 = 9 possible combinations. A seedling matches the parent (Aa and Bb) with probability 1/2 × 1/2 = 1/4. Most seedlings differ from the parent and from each other.

    • A simulation: bean-draw offspring for a fictional animal

      The Snorkid is a fictional animal with 3 genes on 3 chromosome pairs, and both parents are Aa Bb Cc. For each gene, each parent has a bag with one dark bean (the capital-letter allele) and one white bean. To make a sexual offspring, draw one bean from each bag of each parent without looking. To make an asexual offspring, copy both beans of every bag of one parent. A group made 16 offspring each way (invented results): asexual, 16 of 16 were Aa Bb Cc; sexual, 3 of 16 were Aa Bb Cc and the other 13 differed.

      Result: Model prediction for a sexual offspring to match a parent: 1/2 for each gene, so 1/2 × 1/2 × 1/2 = 1/8, and 16 × 1/8 = 2 expected. Observed 3 of 16 = 18.75%, near the predicted 12.5% for so few offspring. Asexual offspring: 100% identical, as the model predicts.

    After each example, ask: "How many parents? Did the offspring get copies of all the parent's genes or half from each parent? What does the model predict about how alike the offspring are?" Use Example 2 to show that a Punnett square predicts chances, not exact counts.

  3. Guided Practice10-15 minutes

    Pairs build two Punnett squares and one asexual model. In cats, the allele for short hair (L) is dominant to the allele for long hair (l).

    1. Cross 1: two short-haired cats, both Ll. Draw the Punnett square and write the chance that a kitten has long hair.
    2. Cross 2: a short-haired Ll cat and a long-haired ll cat. Draw the square and write the chance of a long-haired kitten.
    3. For Cross 2, predict how many long-haired kittens to expect in a litter of 4. Explain why a real litter of 4 could have 0, 1, 3 or 4 long-haired kittens.
    4. Garlic is usually grown by planting single cloves from a bulb. A farmer plants all 10 cloves from one bulb. Draw a model that shows the genes of the parent plant and the 10 new plants.
    5. Write two sentences comparing how alike the kittens and the garlic plants are, and why.
  4. Independent Practice10-15 minutes

    Each student analyzes invented data about the Bloomworm, a fictional sea worm that can split in two (asexual) or mate (sexual). Both parent worms carry two different alleles for each of 4 genes. Scientists recorded whether each offspring had exactly the same allele pairs as its parents for all 4 genes.

    Independent practice data (invented): 20 Bloomworm offspring of each kind
    How the offspring were madeSame allele pairs as the parents for all 4 genesDifferent in at least one gene
    Splitting (asexual)200
    Mating (sexual)218

    Students find the percent of each group that matched the parents, use the model (1/2 for each gene) to predict the chance that a sexual offspring matches, and explain in a paragraph why the two groups differ so much. They end with one prediction: what would happen to the match rate if the worms differed in 8 genes instead of 4?

  5. Closure5 minutes

    Exit ticket: "Draw a quick model of one asexual and one sexual reproduction from today. Label where the offspring's genes came from, and write one sentence on why only one kind gives variation." Return to the warm-up photos and ask students to explain the plants and the kittens with their model.

Differentiation Strategies

For Struggling Students

  • Provide a Punnett square template with the parent alleles already in place, and color-code the dominant allele
  • Use paper strips for chromosomes so students can physically copy (asexual) or split (sexual) them
  • Give a sentence frame: "In ___ reproduction there is/are ___ parent(s), so the offspring get ___, which means they are ___."

For Advanced Students

  • Ask students to count the possible combinations for 4 genes when both parents are Aa Bb Cc Dd (3 × 3 × 3 × 3 = 81)
  • Have students pool class simulation data and explain why bigger samples land closer to the Punnett prediction
  • Ask students to argue when a farmer would choose cuttings and when a plant breeder would choose seeds

Assessment Guidance

What to Look For

Check that students explain the cause, not just the outcome: asexual offspring are identical because all chromosomes are copied from one parent; sexual offspring vary because each parent passes on a random one of each chromosome pair. Look for correct Punnett squares that list one parent's alleles on each side. Listen for students who treat Punnett predictions as exact counts or who think a sexual offspring is a half-and-half blend of its parents.

02

Classroom Activities

3 Activities

1

Bean Draw: Building Snorkid Offspring

25 minGroups of 3

Groups simulate asexual and sexual reproduction for the fictional Snorkid. Each parent has three paper bags, one for each gene, and each bag holds one dark bean (dominant allele) and one white bean (recessive allele).

Procedure

  • Trait key: gene A, ears (at least one dark bean: pointed; two white: round); gene B, tail (dark: striped; two white: plain); gene C, body (dark: green; two white: orange).
  • Asexual round: one parent "buds". Copy both beans of each of its bags onto the record sheet. Make 10 offspring this way.
  • Sexual round: without looking, draw one bean from each bag of parent 1 and one from each bag of parent 2. Record the pair for each gene, put the beans back and shake the bags. Make 10 offspring.
  • Draw one offspring of each kind. Safety: dried beans are not food; do not eat them, and pick up any that fall.

Sample Data (invented)

Eight groups pooled 80 sexual offspring: 11 had the same allele pairs as the parents for all three genes (Aa Bb Cc). All 80 asexual offspring matched their parent.

Discussion Questions

  • The model predicts that 1 in 8 sexual offspring match the parents. How many of 80 is that, and how close was the class?
  • Why do you put the beans back and draw without looking? What part of real reproduction does that stand for?
  • Did any sexual offspring show a trait that neither parent showed, such as an orange body? Explain how.

Modification for Distance Learning

Students use two coins per parent (heads for the dark allele) or an online random picker, and share results in a class spreadsheet.

2

Cuttings and Seeds: A Coleus Investigation

20 min, then 2 weeks of observationPairs

Coleus plants have leaves with bold color patterns. Pairs make stem cuttings from one named-variety plant (asexual reproduction by people) and compare them with seedlings the teacher grew from a mixed seed packet (sexual reproduction).

Procedure

  • With blunt scissors, cut a 10 cm stem tip just below a leaf joint. Remove the lowest leaves and stand the stem in a cup of water labeled with your names.
  • Sketch and describe the leaf pattern of the parent plant and of 10 seedlings: colors, edge shape and markings.
  • Over the next 2 weeks, check the cuttings for roots and compare their new leaves with the parent's leaves.
  • Safety: wash hands after handling the plants, and keep the plants away from pets at home.

Sample Data (invented)

All 12 rooted cuttings in one class grew leaves with the parent's pattern. The 10 seedlings showed 6 different leaf patterns.

Discussion Questions

  • Explain with a model why the cuttings match the parent plant.
  • Why do the seedlings differ from each other, even though they came from one seed packet of one kind of plant?
  • A garden center wants 200 plants that all look exactly like its best coleus. Which method should it use, and why?

Modification for Distance Learning

With an adult's permission, students root a cutting from a houseplant such as pothos in water, or use the teacher's photo series of the class plants.

3

Model Critique: Find and Fix the Error

15 minGroups of 3-4

Groups receive three models drawn by fictional students. Each model contains one error. Groups find the error, explain why it is wrong with evidence from the other models on this page, and redraw it correctly.

The Three Models

  • Model A (asexual): a parent sea anemone with 4 chromosome pairs splits in two, and the drawing gives each new anemone 2 chromosome pairs.
  • Model B (sexual): a diagram of two parent rabbits in which the baby rabbit gets all its chromosomes from the mother.
  • Model C (Punnett square): a square for Bb × bb in which the student wrote "Bb" across the top and "Bb" down the side.

Discussion Questions

  • How many chromosome pairs should each new anemone in Model A have, and why?
  • How should Model B change, and what does the change mean for variation among baby rabbits?
  • Fix Model C. What is the chance of a bb offspring in the corrected square?

Challenge Variation

Groups draw their own model with one hidden error and trade it with another group to find and fix.

03

Diagrams & Visual Aids

2 diagrams

Diagram 1: A Model of Gene Transmission in Asexual and Sexual Reproduction

Asexual: one parent Sexual: two parents A a B b Parent: Aa Bb copies of all genes A a B b Aa Bb A a B b Aa Bb A a B b Aa Bb All offspring identical A a B b Parent 1: Aa Bb A a b b Parent 2: Aa bb each parent gives one allele from each pair A A B b AA Bb A a b b Aa bb a a B b aa Bb Offspring vary Each bar is one chromosome. Letters are alleles (versions) of gene A and gene B.
Left: in asexual reproduction one parent passes on copies of all its chromosomes, so every offspring has the same alleles (Aa Bb). Right: in sexual reproduction each parent passes on one chromosome from each pair, chosen at random, so offspring get new combinations. The three offspring shown are three of the possible combinations from these parents.

Diagram 2: Punnett Square for Two Ww Squash Plants (Example 2)

Parent 2 (Ww): pollen Parent 1 (Ww): eggs W W w w WW white fruit Ww white fruit Ww white fruit ww yellow fruit WW: 1 box of 4 Ww: 2 boxes of 4 ww: 1 box of 4 White fruit: 3 in 4 Yellow fruit: 1 in 4 W (white) is dominant to w (yellow). Each box is one equally likely outcome.
Each parent passes on W or w with equal chance. The four boxes are equally likely, so 1 in 4 offspring are expected to be WW, 2 in 4 Ww and 1 in 4 ww. Because W is dominant, 3 in 4 are expected to have white fruit and 1 in 4 yellow fruit.

04

Homework Assignment

~30 min

MS-LS3-2 Homework: Identical or Varied Offspring?

Directions: All data sets are invented for practice. Draw models (diagrams or Punnett squares) where asked, and in every explanation say how many parents there are and where the offspring's genes come from.

Part 1: Asexual or Sexual? (Problems 1-3)

  1. A quaking aspen tree can send up new trunks from its roots, so a whole hillside of trunks can be one connected organism, called a clone. In fall, all the trunks of one clone turn yellow within the same few days, while a clone on the next hillside may turn a week later. (a) Is growing new trunks from roots asexual or sexual reproduction? (b) Use a model to explain why the trunks of one clone change color together. (c) Aspens also make seeds from flowers that are pollinated by wind. Predict how a group of aspens grown from seed would compare in fall, and explain.
  2. In many sheep breeds, the allele for white wool (W) is dominant to the allele for black wool (w). A Ww ram is mated with ww ewes. (a) Draw the Punnett square. (b) What is the chance that a lamb has black wool? (c) How many black lambs would you expect among 12 lambs? (d) One farm got 4 black lambs out of 12. Does this mean the model is wrong? Explain.
  3. The Glimmer snail is a fictional snail in which a spiral shell (S) is dominant to a flat shell (s). Glimmer snails can mate, and they can also reproduce by splitting. (a) Two Ss snails mate. Draw the Punnett square and give the fraction of young expected to be SS, Ss and ss. (b) Of 40 young from such matings, how many would you expect to have flat shells? (c) An Ss snail splits to make 40 young. How many would have flat shells, and why?

Part 2: Simulations and Models (Problems 4-6)

  1. A class ran a bean-draw simulation for one gene with two Aa parents and made 60 offspring (invented results): 12 AA, 34 Aa and 14 aa. (a) Find the percent of each combination. (b) Use a Punnett square to find how many of 60 the model predicts for each. (c) Explain why the results are not exactly equal to the prediction. (d) If one Aa parent had made 60 offspring by budding instead, how many would be Aa?
  2. A rose grower has one rose plant with a perfect deep-red color that buyers love. A plant breeder wants a new rose that resists a leaf disease. (a) Which kind of reproduction should the grower use to make 300 plants with the same color, and how could she do it? (b) Which kind should the breeder use, and why? (c) Use the words "identical genetic information" and "genetic variation" in your answers.
  3. A hydra is a tiny freshwater animal related to jellyfish. In warm water with plenty of food, a hydra grows buds on its side that break off as new hydras. When the water turns cold in fall, many hydras make eggs and sperm instead. (a) Draw a model of each kind of reproduction that shows where the offspring's chromosomes come from. (b) Which offspring will be identical to their parent? (c) Scientists propose that varied offspring are more likely to include some that survive a hard winter. Use your model to explain why variation could help.

Rubric

CriterionFull Credit (2 pts)Partial Credit (1 pt)
ModelsDiagrams and Punnett squares are complete and correct, with one parent's alleles on each sideModel drawn, with one error or missing labels
Cause and EffectExplains that copying all genes gives identical offspring and that half from each parent, at random, gives variationStates the outcome without the cause
Predictions and DataCorrect chances and expected counts, and explains why data scatter around predictionsCorrect chances but counts or the comparison with data missing

05

Quiz: 20 Questions

Interactive, with answers

Instructions

All data sets are invented, and all organisms are plants, animals or fictional species. Draw a Punnett square on scrap paper when a question gives parent alleles. Your score updates as you answer, and Reset quiz clears everything so you or your students can try again.

Multiple choice: pick an option to check it. Short answer: write your answer, then reveal the model answer.

0 of 20 answered · 0 correct

  1. Question 1 of 20 · Multiple Choice

    Which of these is an example of asexual reproduction?

  2. Question 2 of 20 · Multiple Choice

    Why do offspring made by asexual reproduction have genetic information identical to their parent?

  3. Question 3 of 20 · Multiple Choice

    In sexual reproduction, how much of its genetic information does each parent pass to an offspring?

  4. Question 4 of 20 · Multiple Choice

    In a fictional plant, purple flowers (P) are dominant to white flowers (p). A Pp plant is crossed with a pp plant. What is the chance that an offspring has white flowers?

  5. Question 5 of 20 · Multiple Choice

    One parent is AA and the other is aa for one gene. How many different allele combinations can their offspring have for that gene?

  6. Question 6 of 20 · Multiple Choice

    Two Rr plants are crossed, and r is recessive. About how many of 80 offspring would you expect to show the recessive trait?

  7. Question 7 of 20 · Multiple Choice

    Three groups of 10 offspring are described. Which group was most likely made by asexual reproduction?

  8. Question 8 of 20 · Multiple Choice

    Two seedlings grew from seeds of the same two parent plants, but they look different. Which explanation fits the model of sexual reproduction?

  9. Question 9 of 20 · Multiple Choice

    Why can genetic variation among offspring help a population of plants?

  10. Question 10 of 20 · Multiple Choice

    Most bananas sold in stores come from plants grown from shoots of other banana plants, not from seeds. Why does this make a banana farm risky when a new plant disease arrives?

  11. Question 11 of 20 · Multiple Choice

    Two parents are both Aa Bb, with the two genes on different chromosome pairs. What is the chance that an offspring is aa bb?

  12. Question 12 of 20 · Multiple Choice

    In a class simulation with two Aa parents, 12 of 50 offspring were aa. What percent were aa, and how does it compare with the Punnett square prediction?

  13. Question 13 of 20 · Multiple Choice

    Which description is a correct model of sexual reproduction?

  14. Question 14 of 20 · Multiple Choice

    A gardener wants 50 African violet plants that are exactly like her best plant. What should she do?

  15. Question 15 of 20 · Short Answer

    The Fennow is a fictional fox in which a long tail (L) is dominant to a short tail (l). An LL Fennow mates with an Ll Fennow. Draw the Punnett square, give the chance of each allele combination, and predict how many of 8 young would have short tails.

  16. Question 16 of 20 · Short Answer

    Potato farmers usually plant pieces of potatoes, called seed potatoes, instead of true seeds. Use a model to explain why a field planted this way gives very similar plants, and name one risk.

  17. Question 17 of 20 · Short Answer

    In the bean-draw simulation, why must students put the beans back and draw without looking? What would go wrong if a student always chose the dark bean?

  18. Question 18 of 20 · Short Answer

    A student writes: "A seedling gets half its genes from each parent plant, so it must look exactly halfway between its two parents." What is correct in this statement, and what is wrong?

  19. Question 19 of 20 · Short Answer

    A sea anemone can reproduce by splitting down the middle into two anemones. Describe a model that shows where each new anemone's chromosomes come from, and explain whether the two will be genetically identical.

  20. Question 20 of 20 · Short Answer

    A parent that is Aa Bb makes 30 offspring by asexual reproduction. The same kind of organism, crossed Aa Bb × aa bb, makes 40 offspring by sexual reproduction. How many of the 30 asexual offspring are Aa Bb? How many of the 40 sexual offspring would you expect to be aa bb? Explain.

0 of 20 answered · 0 correct

06

Frequently Asked Questions

10 Questions

What does MS-LS3-2 mean?

MS-LS3-2 asks students to build and use models that explain why asexual reproduction makes offspring with identical genetic information and sexual reproduction makes offspring with genetic variation. The code means Middle School, Life Science, core idea 3 (Heredity: Inheritance and Variation of Traits), performance expectation 2.

What grade is MS-LS3-2 taught in?

It is a middle school standard for grades 6-8. Schools usually teach it in grade 7 or 8 life science, often right after MS-LS3-1 on mutations and before natural selection in MS-LS4.

Does MS-LS3-2 have an assessment boundary?

No. MS-LS3-2 has no official Assessment Boundary. The Clarification Statement names the models: Punnett squares, diagrams and simulations that show how genes pass from parent or parents to offspring and why variation results.

Are Punnett squares required for MS-LS3-2?

Punnett squares are one of the models named in the Clarification Statement, along with diagrams and simulations. Students should use at least one of them to explain cause and effect, not only to fill in boxes. One-gene squares with dominant and recessive alleles are enough at this level.

What is the difference between asexual and sexual reproduction?

Asexual reproduction has one parent, and the offspring get copies of all its genes, so they are clones. Sexual reproduction has two parents, and each passes on half its genes, one chromosome of each pair, so the offspring get new combinations.

Why do offspring in the same litter look different?

Each egg and sperm carries a random one of each chromosome pair, so every offspring gets a different mix of the parents' alleles. With many genes, the number of possible combinations is so large that two siblings almost never get the same set, unless they developed from the same fertilized egg.

Are clones always exactly identical?

Clones start with identical genetic information. Rare mutations can make small differences, and the environment, such as light or food, can change how traits develop. That is why a cutting in a dark corner may look paler than its parent even with the same genes.

What simulations work well for MS-LS3-2?

Drawing beans or paper chromosomes from bags, flipping coins for each allele, or using an online random picker all work. The key rule is that each parent passes on one allele per gene at random, and students compare their results with the Punnett square prediction.

Should students use their own families as examples?

No. This page uses plants, animals and fictional organisms, such as the Snorkid and the Bloomworm, so no student's family or traits are put on display. The models work the same way for any sexually reproducing organism.

What misconceptions do students have about reproduction and genes?

Common ones are that offspring are a blend halfway between the parents, that one parent (often the mother) gives more genes, and that a Punnett square gives exact counts. Another is that asexual reproduction only happens in tiny organisms; many plants and some animals, such as hydras and sea anemones, reproduce asexually.